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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Obstructive sleep apnea syndrome in children
1Sleep Disorders Center, Dana Children's Hospital, Tel Aviv Medical Center, Tel Aviv University, Tel Aviv 64239, Israel. tauman@tasmc.health.gov.il
Insights
Childhood obstructive sleep apnea (OSAS) is a growing public health concern. While adenotonsillectomy is a common treatment, its effectiveness varies, necessitating further investigation into surgical outcomes and non-surgical options.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Public Health
Background:
- Childhood obstructive sleep apnea (OSAS) is a distinct condition from adult OSAS, requiring age-specific management.
- Pediatric OSAS, especially with co-occurring obesity, leads to significant health issues and increased healthcare use.
- Adenotonsillectomy (T&A) is the primary treatment, but recent evidence questions its consistent success.
Purpose of the Study:
- To highlight the age-specific considerations for pediatric OSAS diagnosis and treatment.
- To discuss the evolving understanding of T&A outcomes in children.
- To explore the potential of non-surgical interventions for mild or residual pediatric OSAS.
Main Methods:
- Review of current clinical manifestations and polysomnographic findings in pediatric OSAS.
- Analysis of adenotonsillectomy (T&A) efficacy and the need for post-operative evaluation.
- Investigation into non-surgical management strategies for childhood OSAS.
Main Results:
- Pediatric OSAS is a frequent disorder with significant comorbidities, particularly in obese children.
- Adenotonsillectomy (T&A) outcomes may not always meet expectations, suggesting a need for post-T&A polysomnography in certain groups.
- Non-surgical approaches are being explored for milder cases and for residual OSAS post-T&A.
Conclusions:
- Childhood OSAS requires tailored approaches considering its unique clinical profile and age-specific factors.
- The effectiveness of T&A warrants careful evaluation, with potential need for follow-up assessments.
- Non-surgical treatments represent a promising avenue for managing pediatric OSAS, especially in specific patient populations.
Abstract:
The clinical syndrome of obstructive sleep apnea (OSAS) in children is a distinct, yet somewhat overlapping disorder with the condition that occurs in adults, such that the clinical manifestations, polysomnographic findings, diagnostic criteria and treatment approaches need to be considered in an age-specific manner. Childhood OSAS has now become widely recognized as a frequent disorder and as a major public health problem. Pediatric OSAS, particularly when obesity is concurrently present, is associated with substantial end-organ morbidities and increased healthcare utilization. Although adenotonsillectomy (T&A) remains the first line of treatment, evidence in recent years suggests that the outcomes of this surgical procedure may not be as favorable as expected, such that post-T&A polysomnographic evaluation may be needed, especially in high-risk patient groups. In addition, incorporation of nonsurgical approaches for milder forms of the disorder and for residual OSAS after T&A is now being investigated.
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