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Updated: May 31, 2026

Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice
Published on: May 13, 2019
Relief of right ventricle to pulmonary artery conduit compression by chest wall resection
Brian E Kogon1, Ashish Jain, Jonathan McGuinness
1Departments of Cardiothoracic Surgery Cardiology, Emory University, 1450 Clifton Road NE, Atlanta, GA 30322, USA. Brian_kogon@emoryhealthcare.org
Abstract:
Many congenital heart defects require reconstruction of the right ventricular outflow tract utilizing a right ventricle to pulmonary artery conduit. One of the challenges with these conduits is the development of conduit stenosis. This phenomenon is quite common and typically results from a combination of progressive calcification, fibrosis, and/or the relative size mismatch that occurs with patient growth. However, extrinsic compression is much less common and a much more difficult problem to address. Chest wall resection and reconstruction is an option for alleviating external conduit compression that provides good results.
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