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1Pediatric and Congenital Adult Cardiac Surgery Unit, S Orsola-Malpighi University Hospital, Bologna, Italy. manuangeli@libero.it
Insights
This study evaluates crystalloid Custodiol cardioplegia for myocardial protection in newborns undergoing arterial switch operation (ASO) for transposition of the great arteries (TGA), assessing early and late outcomes.
Area of Science:
- Pediatric Cardiac Surgery
- Cardiovascular Surgery
- Myocardial Protection
Background:
- Pediatric cardiac surgery aims for definitive repair at birth to mitigate risks of palliative surgery and long-term cardiac dysfunction.
- Newborns undergoing complex cardiac defect repair face prolonged myocardial ischemia.
- Effective myocardial protection is crucial for successful cardiac surgical procedures and preventing iatrogenic injury.
Purpose of the Study:
- To assess the impact of crystalloid HKT Custodiol cardioplegia on myocardial protection in neonates.
- To evaluate the early and late outcomes of newborn patients undergoing arterial switch operation (ASO) for transposition of the great arteries (TGA).
Main Methods:
- Infusion of crystalloid HKT Custodiol cardioplegia.
- Surgical intervention: Arterial Switch Operation (ASO).
- Patient population: Newborns with Transposition of the Great Arteries (TGA).
Main Results:
- (Results not provided in the abstract)
Conclusions:
- (Conclusions not provided in the abstract)
Abstract:
Technical success and absence of iatrogenic injury from inadequate myocardial protection are the foremost targets of every cardiac surgical procedure. The current trends of pediatric cardiac surgery are aimed to achieve definitive repair of complex cardiac defects at birth as to avoid the risks related with palliative surgery and to reduce the long term impact of the untreated defect on the cardiac function. Thus, even newborn patients are exposed to a prolonged time of myocardial ischemia. The aim of this paper is to describe the impact of crystalloid HKT Custodiol cardioplegia infusion on myocardial protection in the early and late outcome of newborn patients who underwent arterial switch operation (ASO) for transposition of the great arteries (TGA).
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