Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hypertension II: Pathophysiology

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...

Hypertension and Regulation of Blood Pressure

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...

Hypertension I: Introduction

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...

Hypertension IV: Drug Therapy and Lifestyle Modifications

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...

Hypertension V: Nursing Management

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Treatment of Chronic Heart Failure in Advanced Chronic Kidney Disease: The HAKA Multicenter Retrospective Real-World Study.

Cardiorenal medicine·2024

Same author

Breast abscess due to Nannizziopsis obscura in an immunocompromised renal transplant patient after travel to Nigeria: case report and review.

BMC infectious diseases·2023

Same author

How to Manage Kidney Transplant Recipients: Deciding Between Glomerular Filtration Rate-Estimating Equations, Creatinine Clearance and Albumin-Creatinine Ratio, or Albumin Excretion.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation·2018

Same author

[Prevalence of vitamin D deficiency in populations at risk for osteoporosis: impact on bone integrity].

Medicina clinica·2002

Search research articles

Related Experiment Video

Updated: May 31, 2026

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension

Published on: May 17, 2024

[Vitamin D and hypertension].

Cayetana Moyano Peregrín¹, Francisca López Rodríguez, Maria Del Mar Castilla Castellano

¹Servicio de Nefrología, Hospital Costa del Sol, Marbella, Málaga, España. tanitak@hotmail.com

Medicina Clinica

|June 28, 2011

Summary

Vitamin D deficiency is common and linked to high blood pressure. This review examines studies on vitamin D supplementation and its effects on hypertension, exploring potential biological mechanisms.

Area of Science:

Endocrinology and Cardiovascular Science

Context:

Vitamin D deficiency (25-hydroxyvitamin D < 20-30 ng/ml) is a widespread issue.
Vitamin D deficiency is associated with various non-musculoskeletal conditions, including autoimmune diseases, cancer, metabolic disorders, and cardiovascular diseases.
Hypertension, a primary cardiovascular risk factor, is also frequently linked to vitamin D deficiency, presenting a dual global health challenge.

Purpose:

To review significant studies investigating the relationship between vitamin D deficiency and hypertension.
To explore the biological mechanisms underlying the connection between vitamin D and blood pressure regulation.
To evaluate the current evidence on the efficacy of vitamin D supplementation in managing hypertension.

Summary:

The article synthesizes research on the interplay between low vitamin D levels and high blood pressure.

More Related Videos

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells

Published on: March 5, 2019

Related Experiment Videos

Last Updated: May 31, 2026

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension

The Antihypertensive Effects and Mechanisms of Huotan Jiedu Tongluo Decoction in Rats with H-Type Hypertension

Published on: May 17, 2024

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells

Published on: March 5, 2019

It discusses potential pathways, such as the renin-angiotensin-aldosterone system and endothelial function, through which vitamin D may influence blood pressure.

Evidence regarding the impact of vitamin D supplementation on hypertensive patients is critically assessed.

Impact:

Highlights the potential role of vitamin D in cardiovascular health beyond its established role in bone metabolism.
Provides a comprehensive overview for clinicians and researchers on the current understanding of vitamin D's influence on hypertension.
Informs potential therapeutic strategies involving vitamin D for managing hypertension and improving cardiovascular outcomes.