Related Experiment Video
Updated: May 31, 2026

09:01
Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
Published on: January 24, 2018
Manipulation under anaesthesia post total knee replacement: long term follow up
David Yeoh1, Nick Nicolaou, Richard Goddard
1Conquest Hospital, East Sussex Hospital Trust Hastings, United Kingdom. david_yeoh@yahoo.co.uk
The Knee
|June 28, 2011
Summary
Manipulation under anesthesia (MUA) effectively improves range of motion in stiff total knee replacements (TKRs). Long-term results show sustained improvement regardless of timing or pre-operative stiffness, with no MUA-related complications.
Area of Science:
- Orthopedic Surgery
- Rehabilitation Medicine
Background:
- Reduced range of motion (ROM) is a common complication after total knee replacement (TKR).
- Manipulation under anesthesia (MUA) is a frequent intervention for stiff TKRs, but long-term outcomes are debated.
Purpose of the Study:
- To evaluate the long-term effectiveness and safety of MUA for improving ROM in stiff TKRs.
- To determine if the timing of MUA or pre-operative ROM affects long-term outcomes.
Main Methods:
- Retrospective review of prospectively collected data from 48 TKR patients undergoing MUA.
- Average follow-up of 7.5 years (range 1-10 years).
- Analysis of ROM changes before and after MUA, and at 1 and 10 years post-procedure.
Main Results:
- MUA significantly improved immediate passive flexion by an average of 44° (p<0.05).
- Mean flexion at 1 year was 87°, and at 10 years was 86°, indicating sustained improvement.
- No significant difference in ROM gain was observed based on the timing of MUA (before/after 12 weeks) or pre-TKR ROM (<90° vs. >90°).
- No complications directly resulted from MUA; one patient required revision for infection unrelated to MUA.
Conclusions:
- MUA is a safe and effective procedure for enhancing ROM in stiff TKRs.
- The benefits of MUA are maintained long-term, irrespective of the timing of intervention or the degree of pre-operative knee stiffness.