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Updated: May 31, 2026

Determination of the Gas-phase Acidities of Oligopeptides
Published on: June 24, 2013
Classification of amino acids and oligopeptides with the use of multi-mode chemical images obtained with ion
Patrycja Ciosek1, Martyna Jańczyk, Wojciech Wróblewski
1Warsaw University of Technology, Faculty of Chemistry, Warsaw, Poland. pciosek@ch.pw.edu.pl
Abstract:
The analysis of amino acids and oligopeptides as important bioanalytes is a significant task in medical diagnostics and proteomic research and currently it is based on chromatographic and electrophoretic methods. In this paper, an approach based on sensor array coupled with titration is proposed for effective recognition of 5 amino acids and 4 oligopeptides. It is shown, that the increase of information gained during measurements of sensors' signals in various pH allows for capturing more data on interaction of amino acids and oligopeptides with various polymeric membranes of potentiometric electrodes used in the array, and that leads to the lowering of classification errors in partial least squares analysis.
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