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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Published on: September 5, 2025

Fatigue and aging with a disability.

Karon F Cook1, Ivan R Molton, Mark P Jensen

  • 1Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA, USA. karonc2@u.washington.edu

Archives of Physical Medicine and Rehabilitation
|June 28, 2011
PubMed
Summary
This summary is machine-generated.

Individuals with disabilities experience significantly higher fatigue levels than the general population, with this disparity increasing with age. This highlights a critical need for further research into fatigue

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Published on: May 31, 2016

Area of Science:

  • Rehabilitation Medicine
  • Disability Studies
  • Epidemiology

Background:

  • Fatigue is a common and debilitating symptom across various chronic conditions.
  • Understanding fatigue prevalence in disability populations compared to the general population is crucial for effective management.

Purpose of the Study:

  • To compare self-reported fatigue levels in individuals with spinal cord injury (SCI), postpolio syndrome (PPS), multiple sclerosis (MS), and muscular dystrophy (MD) against age-matched U.S. population norms.
  • To investigate the relationship between age and fatigue levels within these disability groups compared to the general population.

Main Methods:

  • A survey-based study involving 1836 participants with MD, MS, PPS, and SCI.
  • Fatigue levels were assessed using the PROMIS Depression Short Form and compared with published age cohort means from the U.S. population.
  • Analysis focused on comparing fatigue scores between clinical samples and normative data, and examining age-related trends.

Main Results:

  • Individuals with disabilities reported significantly higher fatigue levels than the general U.S. population.
  • Unlike the general population, where fatigue decreases with age in older cohorts, individuals with disabilities did not show this age-related decline in fatigue.
  • The disparity in fatigue levels between individuals with disabilities and the general population was observed to increase with advancing age.

Conclusions:

  • Individuals with disabilities face a heightened risk of experiencing fatigue, a risk that escalates with age.
  • Further research is essential to elucidate the specific impact of increasing fatigue on the daily functioning and quality of life for aging individuals with disabilities.