Is survivin the potential Achilles' heel of cancer?

Alvaro Lladser1, Carlos Sanhueza, Rolf Kiessling

  • 1Laboratory of Gene Immunotherapy, Fundacion Ciencia para la Vida, Santiago, Chile.

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Adaptive Mechanisms in Cancer Cells02:53

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Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
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Cancer Stem Cells and Tumor Maintenance02:40

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