Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Incidence of Velopharyngeal Insufficiency Surgery Following Orthognathic Surgery in Cleft Lip and Palate.

The Journal of craniofacial surgery·2026

Same author

Evaluating maternal mortality, risk factors, and emergency c-section timing in polytrauma pregnant patients.

The American journal of emergency medicine·2026

Same author

Predictors of Deep Vein Thrombosis in Pediatric Trauma Based on Demographic, Injury, and Clinical Characteristics.

Journal of trauma nursing : the official journal of the Society of Trauma Nurses·2026

Same author

Handoff and Transition of Care Protocols for Critically Ill Surgical Patients: A Concise Review.

Journal of trauma nursing : the official journal of the Society of Trauma Nurses·2026

Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Same author

Shedding Light on Actinic Prurigo: A Systematic Review of Emerging Therapies.

The Australasian journal of dermatology·2025

Same journal

Quantification of cell viability by automated analysis of live cell imaging.

Methods in cell biology·2026

Same journal

Flow cytometry evaluation of cytotoxicity exerted by effector immune cells against tumor cells.

Methods in cell biology·2026

Same journal

Time-lapse confocal laser scanning microscopy analysis of FOOD formation.

Methods in cell biology·2026

Same journal

Screening and identification of protein-protein interaction using proximity labeling.

Methods in cell biology·2026

Same journal

Quantitative high-content profiling of mitochondrial morphology with automated statistical analysis and integrated data visualization.

Methods in cell biology·2026

Same journal

Super-resolution imaging of cell death in Drosophila tissues via expansion and pan-expansion microscopy.

Methods in cell biology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 31, 2026

Generation of Dynamical Environmental Conditions using a High-Throughput Microfluidic Device

Generation of Dynamical Environmental Conditions using a High-Throughput Microfluidic Device

Published on: April 17, 2021

Microfluidic systems for live cell imaging.

Philip Lee¹, Terry Gaige, Paul Hung

¹CellASIC Corporation, Hayward, California, USA.

Methods in Cell Biology

|June 28, 2011

Summary

This summary is machine-generated.

Microfluidic systems enhance live cell imaging with better cell culture and flow control. This technology offers a versatile platform for diverse biological applications, becoming increasingly common in research.

More Related Videos

Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation

Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation

Published on: December 6, 2013

Microfluidic Approach to Resolve Simultaneous and Sequential Cytokine Secretion of Individual Polyfunctional Cells

Microfluidic Approach to Resolve Simultaneous and Sequential Cytokine Secretion of Individual Polyfunctional Cells

Published on: March 8, 2024

Related Experiment Videos

Last Updated: May 31, 2026

Generation of Dynamical Environmental Conditions using a High-Throughput Microfluidic Device

Generation of Dynamical Environmental Conditions using a High-Throughput Microfluidic Device

Published on: April 17, 2021

Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation

Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation

Published on: December 6, 2013

Microfluidic Approach to Resolve Simultaneous and Sequential Cytokine Secretion of Individual Polyfunctional Cells

Microfluidic Approach to Resolve Simultaneous and Sequential Cytokine Secretion of Individual Polyfunctional Cells

Published on: March 8, 2024

Area of Science:

Biotechnology
Cell Biology
Microfluidics

Background:

Microfluidic systems offer significant advantages for live cell imaging.
These benefits include optimized micro-environments, precise control over fluid dynamics and exposure, and seamless integration with high-resolution microscopy.

Purpose of the Study:

To present a novel approach for designing and engineering microfluidic cell culture environments.
To demonstrate the integration of these systems with standard laboratory tools and protocols.
To highlight an application-specific design concept utilizing a shared fabrication process for diverse biological applications.

Main Methods:

Design and engineering of microfluidic devices for cell culture.
Interfacing microfluidic systems with existing laboratory equipment and workflows.
Development of a shared fabrication process for multiple microfluidic products.

Main Results:

Successful design and engineering of microfluidic cell culture environments.
Demonstrated compatibility with standard laboratory tools and protocols.
A versatile fabrication approach enabling multiple product outputs for different biological applications.

Conclusions:

Microfluidic cell culture technology provides a powerful platform for live cell imaging.
The presented application-specific design concept offers a scalable and adaptable solution.
The widespread adoption of microfluidic cell culture is anticipated as advanced in vitro models become more prevalent.