Related Experiment Video
Updated: May 31, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Mindfulness, response styles and dysfunctional attitudes in bipolar disorder
Tania Perich1, Vijaya Manicavasagar, Philip B Mitchell
1Black Dog Institute, Hospital Rd, Randwick, NSW, Australia. t.perich@unsw.edu.au
Individuals with bipolar disorder exhibit distinct cognitive patterns, specifically higher scores on Dependency and Achievement scales, compared to those with major depressive disorder or no mood disorder history. These findings highlight cognitive differences in bipolar disorder.
Area of Science:
- Psychiatry
- Cognitive Psychology
- Clinical Psychology
Background:
- Investigating cognitive differences in mood disorders.
- Comparing bipolar disorder, major depressive disorder, and healthy controls.
Purpose of the Study:
- To examine variations in mindfulness, dysfunctional attitudes, and response styles.
- To identify specific cognitive markers differentiating bipolar disorder.
Main Methods:
- 192 participants: 90 with bipolar disorder, 36 with remitted major depressive disorder, 66 controls.
- Assessed mindfulness, dysfunctional attitudes, and response styles.
- Controlled for mood state and anxiety comorbidity.
Main Results:
- No significant differences in mindfulness or response styles across groups.
- Bipolar disorder group showed higher scores on Dependency and Achievement subscales of the Dysfunctional Attitudes Scale.
- Cognitive styles significantly differed between bipolar disorder and other groups.
Conclusions:
- Bipolar disorder is associated with specific cognitive styles (Dependency, Achievement) on the Dysfunctional Attitudes Scale.
- Limitations include small sample sizes for control and remitted major depressive disorder groups.
- Further research is needed to understand the impact of these cognitive domains on bipolar disorder's course and outcome.
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