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Updated: May 31, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Papillary thyroid cancer in thalassaemia
Maria Rita Govoni1, Monica Sprocati, Elena Fabbri
1Dept. of Reproduction and Growth, St. Anna Hospital, Corso Giovecca, Ferrara, Italy. mr.govoni@ospfe.it
Abstract:
Thyroid cancer is the most frequent endocrine neoplasm in the general population. Its incidence is 5-10/100,000 per year, with an annual death rate of 0.2-1.2/100,000 in men and 0.4-2.8/100,000 in women. In thalassaemia patients the frequency of this disease is unknown. In this paper we describe five cases of papillary thyroid cancer in thalassaemia patients followed at the Day Hospital for Thalassaemia and Haemoglobinopathies, in Ferrara, Italy. We consider the possible key role of iron as a carcinogenic agent and we also discuss the practical implications of our clinical observations.
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