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Updated: May 31, 2026

Simultaneous Whole-cell Recordings from Photoreceptors and Second-order Neurons in an Amphibian Retinal Slice Preparation
Published on: June 1, 2013
In vivo evidence that retinal bipolar cells generate spikes modulated by light
Elena Dreosti1, Federico Esposti, Tom Baden
1MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK.
Abstract:
Retinal bipolar cells have been assumed to generate purely graded responses to light. To test this idea we imaged the presynaptic calcium transient in live zebrafish. We found that ON, OFF, transient and sustained bipolar cells are all capable of generating fast 'all-or-none' calcium transients modulated by visual stimulation.
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