Evolution of antimicrobial resistance of Acinetobacter baumannii in a university hospital
G F Viana1, S M dos Santos Saalfeld, L B Garcia
1Department of Basic Health Sciences, State University of Maringá, Maringá, Paraná, Brazil.
Aims:
To investigate the susceptibility pattern and the molecular epidemiology of Acinetobacter baumannii isolates in two periods (1994-1996 and 2004-2007) in Londrina University Hospital.
Methods And Results:
Antimicrobial susceptibility of 150 A. baumannii isolates was assessed by disc diffusion and agar dilution methods. Genetic similarity amongst the isolates was evaluated by ERIC-PCR. Resistance of A. baumannii to carbapenems increased from 2% (1994-1996) to 73% (2004-2007). Thirty-eight clones were detected.
Conclusions:
The results of the study suggest that the high prevalence of carbapenem resistance amongst Acinetobacter baumannii organisms in this institution is not caused by the spread of a predominant clone.
Significance And Impact Of The Study:
This work reinforces the importance monitoring antimicrobial susceptibility rates.
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