Related Experiment Video
Updated: May 31, 2026
Ultrasound Cyclo Plasty in Eyes with Glaucoma
Published on: January 26, 2018
Contact transcleral photodynamic cyclo-suppression in human eyes: a feasibility study
Spyridon K Charisis1, Efstathios T Detorakis, Vania S Vitanova
1University Hospital of Heraklion, Department of Ophthalmology, Crete, Greece.
Objective:
To evaluate the safety and efficacy of contact transcleral ciliary body photodynamic treatment (CB-PDT) with verteporfin in human eyes.
Design:
Prospective interventional case series.
Participants:
Five glaucomatous blind eyes of 5 patients.
Methods:
Verteporfin (6 mg/m(2)) was infused in bolus and then the ciliary body was irradiated transclerally with a fibre optic device. Twelve spots were placed 360° and 0.5 mm behind the sclerocorneal limbus. Laser power was 80 mW and irradiation time was 3 minutes.
Results:
The average intraocular pressure reduction was 30% after the first month and remained below pre-treatment levels throughout a 3-month follow-up. No serious adverse events were reported.
Conclusions:
CB-PDT for refractory glaucoma was safe and efficient in human eyes; larger studies are required to evaluate its possible clinical role.
