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Stimulation of growth hormone and corticotropin release by angiotensin II in man

E C degli Uberti1, G Trasforini, A Margutti

  • 1Institute of Clinical Medicine, University of Ferrara, Italy.

Metabolism: Clinical and Experimental
|October 1, 1990
PubMed

The intravenous (IV) infusion of angiotensin II (AII) was administered to seven healthy male volunteers in a randomized placebo-controlled study. As expected, AII induced a significant increase in blood pressure and plasma aldosterone concentrations. AII caused a significant increase in corticotropin (ACTH) and growth hormone (GH) release, but had no effect on the release of thyrotropin (TSH) and prolactin (PRL). These findings suggest that peripherally circulating AII might influence ACTH and GH secretion in humans.

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