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Updated: May 31, 2026

A Quantitative Cell Migration Assay for Murine Enteric Neural Progenitors
Published on: September 18, 2013
Embryology of the hindgut
Dietrich Kluth1, Henning C Fiegel, Roman Metzger
1Department of Pediatric Surgery, University of Leipzig, Leipzig, Germany. dietrich.kluth@medizin.uni-leipzig.de
Abstract:
Normal and abnormal development of the hindgut is still in debate. Normal development of the hindgut critically depends on the cloacal membrane. In this study, scanning electron microscopy of staged rat embryos between the gestational days 10-15 was performed to show the normal development of the hindgut and the abnormal development in Danforth's short tail (SD) mice. Our studies in normal and abnormal development indicate that the embryonic cloaca never passes through a stage that is similar to any form of anorectal malformation in neonates, including the so-called "cloacas" in females. To explain the abnormal development in anorectal malformations, further studies are mandatory.
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