Metabolic syndrome in children with and without developmental coordination disorder
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Published on: July 27, 2022
Gita Wahi1, Paul J LeBlanc, John A Hay
1Department of Pediatrics, McMaster University, Hamilton, ON, Canada.
Insights
Children with developmental coordination disorder (DCD) show higher rates of abdominal obesity, elevated triglycerides, and blood pressure. These factors increase their risk for metabolic syndrome (MetS) compared to peers.
Area of Science:
- Pediatrics
- Metabolic Health
- Developmental Disorders
Background:
- Children with developmental coordination disorder (DCD) exhibit higher obesity rates than typically developing children.
- This increased obesity risk may predispose them to metabolic syndrome (MetS).
Purpose of the Study:
- To investigate the prevalence of MetS and its individual components in children with and without DCD.
- To identify specific metabolic risk factors associated with DCD in children.
Main Methods:
- A nested case-control study involving 63 children with probable DCD (pDCD) and 63 controls, identified using the Movement Assessment Battery for Children (M-ABC-2).
- Metabolic syndrome was diagnosed based on International Diabetes Federation (IDF) criteria.
- Key metrics included abdominal obesity, serum triglycerides, blood pressure, and other MetS components.
Main Results:
- Eleven children met MetS criteria; 8 were in the pDCD group (72.3%) versus 3 controls (27.3%).
- Abdominal obesity was significantly higher in the pDCD group (46.0%) compared to controls (15.9%).
- Elevated serum triglycerides and higher blood pressure (systolic and diastolic) were observed in children with pDCD.
Conclusions:
- Children with probable DCD demonstrate a higher prevalence of key metabolic syndrome risk factors, including abdominal obesity, elevated triglycerides, and hypertension.
- These findings suggest that children with DCD are at an elevated risk for developing metabolic syndrome earlier than their peers.
- Early identification and intervention for metabolic health in children with DCD are warranted.
Abstract:
Children with developmental coordination disorder (DCD) have higher rates of obesity compared to children with typical motor development, and, as a result may be at increased risk for developing metabolic syndrome (MetS). The purpose of this study was to determine the presence of MetS and its components among children with and without DCD. This nested case-control study classified 63 children scoring below the 16th percentile on the Movement Assessment Battery for Children (M-ABC-2) as probable DCD (pDCD), and 63 controls, all of whom scored above the 16th percentile. Metabolic syndrome was defined using the International Diabetes Federation (IDF) criteria. Eleven children met the criteria for MetS; 8 (72.3%) with pDCD and 3 (27.3%) controls (p = 0.115). Abdominal obesity was found in 39 (30.9%) of children, 29 (46.0%) with pDCD and 10 (15.9%) controls (p < 0.01). Serum triglycerides were higher in pDCD compared to controls, 91.9 mg/dl (63.1) vs. 67.7 mg/dl (33.3) in the control group, p = 0.001. Blood pressure was also significantly higher in the pDCD group, mean systolic BP (110 vs. 105 mmHg, p = 0.01) and mean diastolic BP (69 vs. 65 mmHg, p = 0.01). There were no statistically significant differences between the groups for other components of MetS. The higher prevalence of abdominal obesity and elevated triglycerides and blood pressure in children with pDCD may put them at risk of meeting all criteria of MetS earlier then their peers.
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