The status of coronary artery lesions in patients with conduction disturbance
Shipeng Wei1, Lihua Zhong, Song Chen
1Department of Cardiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Insights
Coronary artery lesions differ in patients with conduction disturbances compared to controls. Type IV lesions were most common in patients with conduction issues, unlike controls where Type III and IV were prevalent.
Area of Science:
- Cardiology
- Electrophysiology
- Interventional Cardiology
Background:
- Conduction disturbances are linked to coronary artery lesions, but lesion types are not well-defined.
- Understanding these associations is crucial for patient management.
Purpose of the Study:
- To investigate coronary artery lesion characteristics in patients with conduction disturbances.
- To compare lesion prevalence between patients with and without conduction disturbances.
Main Methods:
- Coronary angiography was performed on 107 symptomatic patients undergoing pacemaker implantation.
- Lesion severity and pathological anatomy were assessed.
- An age-matched control group of 80 individuals with coronary artery lesions but no conduction disturbance was included.
Main Results:
- Third-degree atrioventricular block (AVB) and sick sinus syndrome were common conduction disturbances.
- Type IV coronary artery lesions were most prevalent (51.3%) in patients with conduction disturbances.
- Type III and IV lesions were most common in the control group, differing significantly from the patient group.
Conclusions:
- Coronary artery lesion types significantly differ between patients with and without conduction disturbances.
- Left anterior descending and right coronary arteries are frequently involved in patients with conduction disturbances.
Background:
Conduction disturbances are related to coronary artery lesions. However, the types of coronary artery lesions prevalent among patients having conduction disturbances are still uncertain.
Objective:
To investigate the status of coronary artery lesions in 107 consecutive symptomatic patients admitted to the fourth affiliated hospital of Harbin Medical University between 2005 and 2009 to receive pacemaker implantation.
Methods:
All of the patients previously underwent coronary angiography for detection of symptoms related to coronary artery disease. The coronary angiographic study included stenosis severity and classification of pathological anatomy. Eighty patients had obvious coronary artery lesions; therefore, 80 age-matched individuals with more than 50% coronary artery lesions but without conduction disturbance composed the control group. The differences in the status of coronary artery lesions were studied between the groups.
Results:
Third-degree atrioventricular block (AVB) was diagnosed in 51 patients (47.7%); 49 (45.8%) had sick sinus syndrome and 7 (6.5%) had Mobitz II, second-degree AVB. Individuals with type IV lesions accounted for 51.3% of the patients with coronary artery lesions, whereas those with type II lesions had the second highest prevalence (26.3%). Patients with type III and I lesions accounted for 15 and 7.5% of the cases, respectively. This distribution was significantly different from those in the control group in which the most prevalent types were type III and IV (46.8 and 31.6%, P < 0.05, respectively).
Conclusion:
The prevalence of coronary lesion types was different for patients with conduction disturbance from those without it; both left anterior descending artery and right coronary artery appeared to be involved in patients with conduction disturbance.
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