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Updated: May 31, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
New approaches to disease mapping in admixed populations
Michael F Seldin1, Bogdan Pasaniuc, Alkes L Price
1Department of Biochemistry and Molecular Medicine, University of California Davis, Davis, California, USA. mfseldin@ucdavis.edu
None:
Admixed populations such as African Americans and Hispanic Americans are often medically underserved and bear a disproportionately high burden of disease. Owing to the diversity of their genomes, these populations have both advantages and disadvantages for genetic studies of complex phenotypes. Advances in statistical methodologies that can infer genetic contributions from ancestral populations may yield new insights into the aetiology of disease and may contribute to the applicability of genomic medicine to these admixed population groups.
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