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Updated: May 31, 2026

Electrophysiological Assessment of Murine Atria with High-Resolution Optical Mapping
Published on: February 22, 2018
Current concepts in pacing 2010-2011: the right and wrong way to pace
Simon Modi1, Andrew Krahn, Raymond Yee
1Arrhythmia Service, London Health Sciences Centre, London, ON, Canada, simonmodi@gmail.com.
Single chamber atrial pacing (AAI/R) should be replaced by dual chamber pacemakers (DDD/R) to minimize ventricular pacing. DDD/R devices are appropriate for elderly patients with atrioventricular block, and right ventricular septal lead placement is recommended.
Area of Science:
- Cardiology
- Biomedical Engineering
Background:
- Permanent cardiac pacemakers have been used for over 50 years, with evolving technology necessitating clinical practice adaptation.
- Pacing mode choice remains controversial, with significant regional variations in practice.
- Evidence-based medicine scrutinizes the roles and benefits of individual pacemaker technologies.
Purpose of the Study:
- To advocate for the abandonment of single chamber atrial pacing (AAI/R) in favor of dual chamber pacemakers (DDD/R) with advanced algorithms.
- To emphasize the individualized approach to pacemaker selection, particularly for elderly patients with atrioventricular (AV) block.
- To recommend optimal lead placement strategies for right ventricular (RV) pacing and the consideration of cardiac resynchronization therapy (CRT).
Main Methods:
- This opinion statement is based on a critical review of current clinical practices and evidence from randomized clinical trials.
- The authors present their expert opinion on pacing mode selection, lead placement, and the role of CRT.
- The discussion considers patient-specific factors, including age and physiological status.
Main Results:
- Single chamber atrial pacing (AAI/R) is considered an anachronism and should generally be abandoned.
- Dual chamber pacemakers (DDD/R) with algorithms minimizing ventricular pacing are preferred.
- Randomized trials have not shown clear benefits of DDD/R over other modes in elderly AV block patients, but individualized care justifies DDD/R use.
- Right ventricular (RV) septal lead placement is recommended over apical placement.
- Primary cardiac resynchronization therapy (CRT) should be considered for AV block patients with moderate to severely depressed left ventricular systolic function.
Conclusions:
- Dual chamber pacing (DDD/R) with modern algorithms is recommended over single chamber atrial pacing (AAI/R).
- Individualized assessment is crucial for pacemaker selection in all patients, including the elderly with AV block.
- Optimized RV lead placement and consideration of CRT are important for specific patient populations.
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