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Updated: May 31, 2026

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor (SiFA) for Positron Emission Tomography
Published on: January 11, 2020
Labeling strategies with F-18 for positron emission tomography imaging
Yonghong Gu1, Dong Huang, Zhiguo Liu
1Department of Pathology, the Third Xiangya Hospital, Central South University, Changsha, P R China.
Abstract:
The labeling of probes with fluorine-18 [(18)F, β(+); 96.7%] continues to play a considerably important role in the development of positron emission tomography (PET) as a modality for both clinical research and clinical diagnoses. This review summarizes the strategies and recent developments in the fluorine-18 labeling of probes for PET imaging. Problems and issues relating to the practical production of fluorine-18 currently in widespread use are also discussed.
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