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[Rotavirus in newborns less than 24 hours of age]
Insights
Nonsymptomatic newborns were found to be the only positive cases for rotavirus, indicating a 2.11% infection rate. Klebsiella pneumoniae was the primary bacteria identified in symptomatic infants.
Area of Science:
- Virology
- Microbiology
- Neonatal Health
Context:
- A 22-month study at HUAP (UFF) analyzed 687 fecal and meconium samples from newborns.
- Samples were from a baby nursery (n=236) and an outpatient clinic (n=451).
- Testing included ELISA, PAGE, and ME for rotavirus and bacterial cultures.
Purpose:
- To investigate the prevalence of rotavirus and common bacterial infections in newborns.
- To explore potential correlations between delivery methods, maternal health, and infant infections.
- To identify etiological agents in both symptomatic and nonsymptomatic newborns.
Summary:
- Rotavirus was detected exclusively in nonsymptomatic newborns, with a prevalence of 2.11%.
- No correlation was found between delivery mode (cesarean or vaginal) or maternal diarrhea and infant diarrhea post-delivery.
- Klebsiella pneumoniae was the predominant bacterium isolated from symptomatic infants in the ward.
Impact:
- Highlights the occurrence of rotavirus in seemingly healthy newborns, suggesting asymptomatic shedding or early-onset infection.
- Underscores the importance of considering rotavirus in neonatal diagnostics, even without overt symptoms.
- Identifies Klebsiella pneumoniae as a significant bacterial pathogen in symptomatic neonates within the studied setting.
Abstract:
During 22 months, 687 samples, including feces and meconium of patients from the baby nursery (group A--236 samples) and from newborns seen in the outpatient clinic (group B--451 samples), were submitted to ELISA, PAGE, and ME, searching for rotavirus and were also cultivated for bacteria, at the HUAP (UFF). Nonsymptomatic newborns were the only positive cases for rotavirus, a rate of 2.11%. Contamination at delivery was suspected, but there was no correlation between either cesarean or vaginal labor and maternal diarrhea with newborn diarrhea after delivery. Klebsiella pneumoniae was the main bacteria in the symptomatic babies from the ward.