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Updated: May 31, 2026

Intestinal Epithelial Regeneration in Response to Ionizing Irradiation
Published on: July 27, 2022
[Therapy of radiation enteritis--current challenges]
Zsolt Baranyai1, Dániel Sinkó, Valéria Jósa
1Uzsoki Utcai Kórház Sebészet-Érsebészeti Osztály Budapest Uzsoki út 29. 1145 Tumorgenetika Biobank Klaszter Budapest. barazso@uzsoki.hu
Abstract:
Radiation enteritis is one of the most feared complications after abdominal and pelvic radiation therapy. The incidence varies from 0.5 to 5%. It is not rare that the slowly progressing condition will be fatal. During a period of 13 years 24 patients were operated due to the complication of radiation enteritis. Despite different types of surgery repeated operation was required in 25% of cases and finally 4 patients died. Analyzing these cases predisposing factors and different therapeutic options of this condition are discussed. Treatment options of radiation induced enteritis are limited; however, targeted therapy significantly improves the outcome. Cooperation between oncologist, gastroenterologist and surgeon is required to establish adequate therapeutic plan.
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