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Updated: May 31, 2026

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Multiple myeloma with lung plasmacytoma.

Rajendra Prasad1, Sanjay Kumar Verma, Rakhi Sodhi

  • 1Department of Pulmonary Medicine, Chatrapati Sahuji Maharaj Medical University (Earlier KGMU), Kanpur, India.

Lung India : Official Organ of Indian Chest Society
|June 30, 2011
PubMed
Summary

Malignant myeloma (MM), a plasma cell cancer, can rarely spread to the lungs, forming a plasmacytoma. This case highlights an uncommon extramedullary manifestation of MM in a non-smoking female patient.

Keywords:
Extramedullary disseminationlungmalignant myeloma

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Area of Science:

  • Oncology
  • Hematology
  • Pulmonology

Background:

  • Malignant myeloma (MM) is characterized by clonal plasma cell proliferation and osteolytic bone lesions.
  • Extramedullary involvement, particularly in the lungs, is an infrequent complication of MM.

Purpose of the Study:

  • To report a rare case of malignant myeloma with extramedullary dissemination to the lung, presenting as a pulmonary plasmacytoma.
  • To contribute to the understanding of uncommon MM presentations.

Main Methods:

  • Case report presentation.
  • Review of clinical presentation, diagnostic findings, and management (details not provided in abstract).

Main Results:

  • A 45-year-old, non-smoking female presented with malignant myeloma.
  • The patient developed an extramedullary plasmacytoma in the lung, an uncommon site for MM dissemination.

Conclusions:

  • Extramedullary plasmacytoma in the lung is a rare but possible manifestation of malignant myeloma.
  • This case underscores the importance of considering unusual MM presentations in clinical practice.