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Relationship between Tei index of myocardial performance and left ventricular geometry in Nigerians with systemic

Adeseye A Akintunde1, Patience O Akinwusi, George O Opadijo

  • 1Division of Cardiology, Ladoke Akintola University of Technology Teaching Hospital, Osogbo, Nigeria. adeseyeakintunde@hotmail.com

Cardiovascular Journal of Africa
|June 30, 2011
PubMed

Insights

The Tei index, measuring heart function, is impaired in hypertensive Nigerians across all left ventricular geometry types. This impairment is most severe in those with concentric and eccentric hypertrophy.

Area of Science:

  • Cardiology
  • Echocardiography
  • Hypertension Research

Background:

  • Left ventricular geometry impacts cardiovascular events and prognosis.
  • The Tei index assesses myocardial performance, reflecting systolic and diastolic dysfunction.
  • Its relation to left ventricular geometry in hypertensive populations is understudied.

Purpose of the Study:

  • To investigate the association between the Tei index and left ventricular geometry in Nigerian hypertensive subjects.
  • To evaluate cardiac function using the Tei index in relation to different hypertensive heart disease patterns.

Main Methods:

  • Echocardiography was performed on 164 hypertensive patients and 64 controls.
  • Subjects were categorized into four left ventricular geometry patterns.
  • The Tei index was calculated as (isovolumic relaxation time + isovolumic contraction time) / ejection time.

Main Results:

  • Hypertensive patients showed significantly higher Tei index values compared to controls.
  • Concentric hypertrophy, concentric remodelling, and eccentric hypertrophy groups had elevated Tei index values.
  • The Tei index correlated with ejection fraction, fractional shortening, and mitral E/A ratio.

Conclusions:

  • All hypertensive subgroups exhibited impaired left ventricular systolic and diastolic function, indicated by the Tei index.
  • The most advanced impairment was observed in patients with concentric and eccentric hypertrophy.
  • Left ventricular geometry is a significant factor in the functional decline associated with hypertension.
Abstract

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