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Updated: May 31, 2026

Rapid PCR Thermocycling using Microscale Thermal Convection
Published on: March 5, 2011
Enhanced droplet spreading due to thermal fluctuations
1Department of Mechanical Science and Engineering, College of Engineering, University of Illinois at Urbana-Champaign, 1206 West Green Street, Urbana, IL 61801, USA. College of Medicine at Urbana-Champaign, University of Illinois at Urbana-Champaign, USA.
Abstract:
The lubrication equation that governs the dynamics of thin liquid films can be augmented to account for stochastic stresses associated with the thermal fluctuations of the fluid. It has been suggested that under certain conditions the spreading rate of a liquid drop on a surface will be increased by these stochastic stresses. Here, an atomistic simulation of a spreading drop is designed to examine such a regime and provide a quantitative assessment of the stochastic lubrication equation for spreading. It is found that the atomistic drop does indeed spread faster than the standard lubrication equations would suggest and that the stochastic lubrication equation of Grün et al (2006 J. Stat. Phys. 122 1261-91) predicts the spread rate.
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