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Related Concept Videos

Aliasing01:18

Aliasing

Accurate signal sampling and reconstruction are crucial in various signal-processing applications. A time-domain signal's spectrum can be revealed using its Fourier transform. When this signal is sampled at a specific frequency, it results in multiple scaled replicas of the original spectrum in the frequency domain. The spacing of these replicas is determined by the sampling frequency.
If the sampling frequency is below the Nyquist rate, these replicas overlap, preventing the original signal...
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.
¹H NMR: Interpreting Distorted and Overlapping Signals01:02

¹H NMR: Interpreting Distorted and Overlapping Signals

Spin systems where the difference in chemical shifts of the coupled nuclei is greater than ten times J are called first-order spin systems. These nuclei are weakly coupled, and their chemical shifts and coupling constant can generally be estimated from the well-separated signals in the spectrum.
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are slanted or...
Lossy Lines and Overvoltages01:22

Lossy Lines and Overvoltages

Transmission-line series resistance and shunt conductance cause three primary effects: attenuation, distortion, and power losses.
Attenuation
When constant series resistance and shunt conductance are present, voltage and current equations are modified. The propagation constant indicates that voltage and current waves consist of both forward and backward traveling components. These waves attenuate as they propagate, with the attenuation factor related to the resistance and conductance. In a...
Interference: Path Lengths01:10

Interference: Path Lengths

Consider two sources of sound, that may or may not be in phase, emitting waves at a single frequency, and consider the frequencies to be the same.
Two special sources may be considered when they are in phase. This can be easily achieved by feeding the two sources from the same source. An example would be synchronizing the two speakers by feeding them with the same source, such as the sound waves produced by a tuning fork. This setup ensures that the two sources have the same frequency and are...
Calibration Curves: Linear Least Squares01:20

Calibration Curves: Linear Least Squares

A calibration curve is a plot of the instrument's response against a series of known concentrations of a substance. This curve is used to set the instrument response levels, using the substance and its concentrations as standards. Alternatively, or additionally, an equation is fitted to the calibration curve plot and subsequently used to calculate the unknown concentrations of other samples reliably.
For data that follow a straight line, the standard method for fitting is the linear...

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A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis (ALS)
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Published on: February 21, 2011

Scle-lp overlap syndrome.

C Shanmuga Sekar1, Reena Rai, N Karthika

  • 1Department of Dermatology, PSG Hospitals, Coimbatore, India.

Indian Journal of Dermatology
|July 1, 2011
PubMed
Summary
This summary is machine-generated.

This case study highlights a rare instance of subacute cutaneous lupus erythematosus overlapping with lichen planus in a 35-year-old female. The condition presented with distinctive scaly, pigmented lesions, confirmed by clinical and laboratory findings.

Keywords:
Subacute cutaneous lupus erythematosuslichen planusoverlap syndrome

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Area of Science:

  • Dermatology
  • Immunodermatology
  • Rheumatology

Background:

  • Subacute cutaneous lupus erythematosus (SCLE) and lichen planus are distinct autoimmune conditions affecting the skin.
  • Overlap syndromes between these two conditions are exceptionally rare in clinical practice.

Purpose of the Study:

  • To report a rare case of co-existing subacute cutaneous lupus erythematosus and lichen planus.
  • To discuss the diagnostic challenges and clinical presentation of this rare dermatological overlap.

Main Methods:

  • Clinical examination of skin lesions.
  • Histopathological analysis of skin biopsy.
  • Direct immunofluorescence studies.
  • Serological testing for antinuclear antibodies (ANA) and anti-Ro antibodies.

Main Results:

  • A 35-year-old female presented with a 2-year history of widespread scaly, annular, and pigmented lesions.
  • Clinical features, histopathology, and immunofluorescence were consistent with an overlap of SCLE and lichen planus.
  • Positive findings for ANA and anti-Ro antibodies supported the diagnosis.

Conclusions:

  • This case underscores the possibility of rare presentations in autoimmune blistering diseases.
  • The combination of SCLE and lichen planus, while rare, should be considered in the differential diagnosis of complex cutaneous conditions.
  • Further research into the immunopathogenesis of such overlaps may be warranted.