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Updated: May 31, 2026

Metacarpal Small Incision for Carpal Tunnel Syndrome
Published on: April 5, 2024
Circumscribed palmar or plantar hypokeratosis: report of an italian case
1Department of Anesthesia, Intensive Care and Dermatological Sciences, Università degli Studi di Milano, IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan via Pace 9, Milan, 20122, Italy.
Abstract:
Circumscribed palmar or plantar hypokeratosis is a rare benign epidermal malformation of the skin. Clinically it shows asymptomatic, well-circumscribed, and depressed erythema persisting for many years on the palms or soles. Its main histopathologic feature shows a characteristic epidermal depression with an abrupt decrement in the thickness of the stratum corneum, with a sharp stair between normal and involved skin. We describe a case of a 68-year-old woman who presented with an erythematous, asymptomatic, well-circumscribed, depressed patch, on the right thenar eminence which had been present for years.
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