Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
Rapid Identification of Pathogens01:25

Rapid Identification of Pathogens

MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exercise, daily physical activity, and age-specific cumulative incidence of mobility decline: an 8-year cohort study of locomotive syndrome.

European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity·2026
Same author

A single-camera video-based assessment of locomotive syndrome using pose-silhouette fusion model.

PLOS digital health·2026
Same author

Feasibility of a Monthly Morphine Milligram Equivalent Metric for Opioid Surveillance Using the National Claims Database of Japan: A Repeated Cross-Sectional Study in a Low-Consumption Setting.

Therapeutic innovation & regulatory science·2026
Same author

Cross-cultural adaptation, reliability, and preliminary construct validity of the Japanese version of the Parkinson's disease pain classification system.

Clinical parkinsonism & related disorders·2026
Same author

HQ1: Do Interventions and Assessments Using Digital Health Services Prevent Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

Geriatrics & gerontology international·2026
Same author

Pain-Related Smoking Expectancies Across Tobacco Product Use Patterns, Including Heated Tobacco Products: Psychometric Validation of the Japanese Pain and Smoking Inventory.

Neuropsychopharmacology reports·2026

Related Experiment Video

Updated: May 31, 2026

A Fast and Reliable Pipeline for Bacterial Transcriptome Analysis Case study: Serine-dependent Gene Regulation in Streptococcus pneumoniae
10:18

A Fast and Reliable Pipeline for Bacterial Transcriptome Analysis Case study: Serine-dependent Gene Regulation in Streptococcus pneumoniae

Published on: April 25, 2015

A new microarray system to detect Streptococcus pneumoniae serotypes.

Yuka Tomita1, Akira Okamoto, Keiko Yamada

  • 1Department of Infectious Disease, Nagoya University Hospital, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. yu-cat@med.nagoya-u.ac.jp

Journal of Biomedicine & Biotechnology
|July 1, 2011
PubMed
Summary

A new DNA microarray accurately identifies Streptococcus pneumoniae serotypes, offering a cost-effective alternative to current methods. This advance aids in monitoring pneumococcal infections and vaccine effectiveness.

More Related Videos

Capsular Serotyping of Streptococcus pneumoniae by Latex Agglutination
09:11

Capsular Serotyping of Streptococcus pneumoniae by Latex Agglutination

Published on: September 25, 2014

Related Experiment Videos

Last Updated: May 31, 2026

A Fast and Reliable Pipeline for Bacterial Transcriptome Analysis Case study: Serine-dependent Gene Regulation in Streptococcus pneumoniae
10:18

A Fast and Reliable Pipeline for Bacterial Transcriptome Analysis Case study: Serine-dependent Gene Regulation in Streptococcus pneumoniae

Published on: April 25, 2015

Capsular Serotyping of Streptococcus pneumoniae by Latex Agglutination
09:11

Capsular Serotyping of Streptococcus pneumoniae by Latex Agglutination

Published on: September 25, 2014

Area of Science:

  • Microbiology
  • Molecular Diagnostics
  • Vaccinology

Background:

  • Streptococcus pneumoniae is a leading cause of severe infections like meningitis and bacteremia.
  • A 23-valent vaccine targets common S. pneumoniae serotypes, but accurate serotyping is challenging.
  • Current serotype testing methods are expensive, subjective, and prone to cross-reactions.

Purpose of the Study:

  • To develop a novel oligonucleotide-based DNA microarray for precise identification of S. pneumoniae serotypes.
  • To evaluate the microarray's performance in distinguishing between vaccine-related serotypes.

Main Methods:

  • Design of an oligonucleotide DNA microarray targeting glycosyltransferase gene sequences specific to S. pneumoniae serotypes.
  • Testing the microarray against 56 S. pneumoniae isolates representing various serotypes.

Main Results:

  • The DNA microarray successfully identified most S. pneumoniae serotypes.
  • A single isolate of serotype 23A could not be distinguished from serotype 23F.

Conclusions:

  • The developed DNA microarray offers a cost-effective and reliable method for S. pneumoniae serotype monitoring.
  • This technology has the potential to improve surveillance of pneumococcal infections and vaccine efficacy.