Limb transplantation and targeted reinnervation: a practical comparison
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Updated: May 31, 2026

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Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
Published on: March 8, 2024
Sonya Paisley Agnew1, Jason Ko, Mauricio De La Garza
1Division of Plastic and Reconstructive Surgery, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA. s-paisley@md.northwestern.edu
Journal of Reconstructive Microsurgery
|July 1, 2011
Abstract:
Limb transplantation and targeted reinnervation are complimentary but very different approaches for restoring function to an upper limb amputee. This article reviews the advantages and limitations of both of these procedures, and highlights the reconstructive obstacles in the treatment of upper limb amputees.
