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Updated: May 31, 2026

Functional and Morphological Assessment of Diaphragm Innervation by Phrenic Motor Neurons
Published on: May 25, 2015
Phrenic nerve palsy and Parsonage-Turner syndrome
John A Odell1, Kathleen Kennelly, John Stauffer
1Section of Cardiothoracic Surgery, Department of Neurology, Mayo Clinic, Jacksonville, Florida 32224, USA. odell.john@mayo.edu
Parsonage-Turner syndrome can cause phrenic nerve palsy, leading to diaphragm dysfunction. Diaphragmatic plication effectively managed symptoms in two patients with this condition.
Area of Science:
- Neurology
- Thoracic Surgery
Background:
- Parsonage-Turner syndrome is an idiopathic neuropathy characterized by acute, severe nerve pain and subsequent muscle weakness.
- Phrenic nerve palsy, a complication of this syndrome, can result in diaphragmatic dysfunction and respiratory compromise.
Observation:
- Two patients presented with symptomatic phrenic nerve palsy attributed to Parsonage-Turner syndrome.
- Clinical presentation included respiratory distress secondary to diaphragmatic paralysis.
Findings:
- Both patients underwent diaphragmatic plication as a surgical management strategy.
- The procedure successfully addressed the diaphragmatic dysfunction and alleviated patient symptoms.
Implications:
- Diaphragmatic plication is a viable surgical option for managing phrenic nerve palsy in the context of Parsonage-Turner syndrome.
- This case report highlights the importance of recognizing and treating this specific complication of Parsonage-Turner syndrome.
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