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Efficient and Consistent Generation of Retinal Pigment Epithelium/Choroid Flatmounts from Human Eyes for Histological Analysis
Published on: October 28, 2022
Retinal detachment in association with pre-eclampsia, eclampsia, and HELLP syndrome
Paulino Vigil-De Gracia1, Luis Ortega-Paz
1Critical Care Unit, Department of Obstetrics and Gynecology, Caja de Seguro Social, Panama, Panama. pvigild@hotmail.com
Summary
Retinal detachment in pre-eclampsia/eclampsia may be linked to HELLP syndrome. Prompt diagnosis and postpartum management ensure complete vision recovery for affected women.
Area of Science:
- Ophthalmology
- Maternal-Fetal Medicine
- Nephrology
Background:
- Pre-eclampsia and eclampsia are serious hypertensive disorders of pregnancy.
- Retinal detachment is a rare but significant complication associated with these conditions.
Observation:
- A review of 28 case reports identified retinal detachment in women with pre-eclampsia/eclampsia.
- The majority of cases were associated with severe pre-eclampsia or HELLP syndrome.
- Retinal detachment was often bilateral and diagnosed postpartum.
Findings:
- HELLP syndrome (hemolysis, elevated liver enzymes, low platelets) appears to be associated with retinal detachment.
- The pathophysiology may involve microangiopathic hemolysis.
- Vision recovery was complete within 2-12 weeks postpartum with clinical management.
Implications:
- Clinicians should consider HELLP syndrome in women with pre-eclampsia/eclampsia and visual disturbances.
- Early diagnosis and management are crucial for visual outcomes.
- Further research into the role of microangiopathic hemolysis in retinal detachment is warranted.
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