Measuring function in older adults with co-morbid illnesses who are undergoing coronary artery bypass graft (CABG)

Monica Parry1, Heather Arthur, Dina Brooks

  • 1Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, 155 College Street, Suite 130, Toronto, ON, Canada. monica.parry@utoronto.ca

Insights

The Human Activity Profile (HAP) better measures functional changes after coronary artery bypass grafting (CABG) surgery in patients with multiple health issues compared to the SF-36v2™ instrument.

Area of Science:

  • Cardiology
  • Rehabilitation Medicine
  • Health Outcomes Research

Background:

  • Measuring functional outcomes after Coronary Artery Bypass Grafting (CABG) surgery presents challenges due to diverse patient abilities and co-morbidities.
  • An increasing number of older patients with multiple health conditions are undergoing CABG surgery.
  • Traditional generic instruments may lack sensitivity in assessing functional differences in this complex patient group.

Purpose of the Study:

  • To compare the efficacy of the Human Activity Profile (HAP) against the Medical Outcome Study Short Form 36 (SF-36v2™) in evaluating functional status post-CABG surgery.
  • To assess the correlation between the Functional Comorbidity Index (FCI) and functional measures in patients undergoing CABG.
  • To determine if the HAP is more sensitive than the SF-36v2™ in detecting functional decrements associated with co-morbidities in CABG patients.

Main Methods:

  • A cohort of 101 patients (84 men, 17 women, mean age 63) undergoing CABG surgery was studied.
  • Patients completed the Human Activity Profile (HAP) and the SF-36v2™.
  • The Functional Comorbidity Index (FCI) was used to quantify co-morbidities, with 82% having three to six co-morbid illnesses.

Main Results:

  • Significant negative correlations were found between FCI scores and HAP's Maximum Activity Score (MAS) (r=-0.32, p=0.002) and Adjusted Activity Score (AAS) (r=-0.29, p=0.004).
  • Higher co-morbidity scores were associated with lower functional capacity as measured by the HAP.
  • A non-significant negative correlation was observed between FCI scores and the SF-36v2™ Physical Component Summary (PCS) (r=-0.19, p=0.07).

Conclusions:

  • The Human Activity Profile (HAP) appears more sensitive than the SF-36v2™ Physical Component Summary (PCS) in detecting functional differences in CABG patients with co-morbidities.
  • Findings suggest that generic functional measures may not adequately capture the nuances of functional status in complex patient populations.
  • Further research is warranted to validate the HAP's utility in diverse populations burdened by co-morbidities.

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