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Updated: May 31, 2026
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
The use of reverse thermosensitive polymer (LeGoo) for temporary vessel occlusion in clampless peripheral vascular
Joseph Shalhoub1, Ankur Thapar, Alun H Davies
1Department of Vascular Surgery, Imperial Vascular Unit, Charing Cross Hospital, Imperial College London, London, UK. j.shalhoub@imperial.ac.uk
Introduction:
There is a need to develop methods of vascular hemostasis, which limit vessel trauma. LeGoo is a reverse thermosensitive polymer (poloxamer) which is a viscous liquid at room temperature, becoming a firm plug at body temperature. We aimed to describe early single center experience in clampless peripheral vascular surgery.
Methods:
Single surgeon experience using LeGoo during peripheral vascular surgery between February and October 2010 was analyzed.
Results:
LeGoo was used in 13 anastomoses in 11 patients. A satisfactory bloodless field without the use of conventional occlusion devices was achieved in 92% of anastomoses. At a median of 36 weeks follow-up, total conduit patency was 91%.
Conclusions:
In this small series, LeGoo was seen to be safe and effective in the provision of a clamp-free bloodless field in the context of peripheral vascular surgery. Prospective comparative study is necessary to determine performance against conventional vascular clamps.
