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A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
Published on: August 14, 2019
Risk factors for prolonged shedding of 2009 H1N1 influenza virus
Yinghu Chen1, Huiju Qiao, Chen Mei Zhang
1Division of Infection Disease, Zhejiang Key Laboratory for Neonatal Disease, Childrens Hospital of Zhejiang University Medical College, Hangzhou 310003, China.
Abstract:
This retrospective study was conducted to estimate the shedding of 2009 H1N1 virus and the risk analysis by review of medical charts, laboratory and radiological findings of all inpatients with confirmed pandemic influenza A (H1N1) at a provincial pediatric hospital. A total of 41 cases attending the inpatient department between 15 November, 2009 to 14 December, 2009 were included. Prolonged and discontinuous shedding of 2009 H1N1 virus (median, 10 days; range, 2 to 24 days) were detected by real-time RT-PCR. The interval from onset of symptom to the start of oseltamivir therapy was an independent risk factor for prolonged virus shedding.
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