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Related Concept Videos

Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of fluid...
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document any history...

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Related Experiment Video

Updated: May 31, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

[Microscopic polyangiitis with renal mass-like lesion: a case report].

Hayato Yamazaki1, Yoshishige Miyabe, Junzo Tomoishi

  • 1Department of Rheumatology, Ome Municipal General Hospital, Japan.

Nihon Rinsho Men'Eki Gakkai Kaishi = Japanese Journal of Clinical Immunology
|July 2, 2011
PubMed
Summary

Microscopic polyangiitis can present as a renal mass, mimicking cancer. Early diagnosis and corticosteroid treatment are crucial for managing vasculitis symptoms.

Related Experiment Videos

Last Updated: May 31, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

Area of Science:

  • Nephrology
  • Rheumatology
  • Pathology

Background:

  • Systemic vasculitis can manifest with diverse clinical presentations, including renal involvement.
  • Distinguishing vasculitis from malignancy is critical for appropriate patient management.

Observation:

  • A 63-year-old man presented with fever, weight loss, peripheral neuropathy, and purpura.
  • A renal mass was identified, initially suspected as renal cell carcinoma.
  • Skin biopsy confirmed vasculitis, but ANCA tests were negative.

Findings:

  • Pathology revealed necrotizing vasculitis and renal infarction, leading to a diagnosis of microscopic polyangiitis.
  • Despite initial misdiagnosis, corticosteroid therapy improved the patient's purpura and neuropathy.

Implications:

  • Renal mass-like lesions associated with vasculitis require careful diagnostic evaluation.
  • This case highlights the importance of considering vasculitis in patients with unexplained renal lesions and systemic symptoms.