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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Heterogeneity of methicillin-sensitive Staphylococcus pseudintermedius strains isolated from diseased dogs

K Garbacz1, L Piechowicz, S Zarnowska

  • 1Department of Medical Microbiology, Medical University of Gdansk, Gdansk, Poland. kasgab@gumed.edu.pl

Polish Journal of Veterinary Sciences
|July 5, 2011
PubMed

Insights

This study analyzed antibiotic resistance in Staphylococcus pseudintermedius strains from dogs. Penicillin resistance was most common, with significant genetic diversity found among the methicillin-sensitive strains.

Area of Science:

  • Veterinary Microbiology
  • Antimicrobial Resistance
  • Canine Bacterial Infections

Background:

  • Staphylococcus pseudintermedius is a common cause of canine skin infections.
  • Understanding antibiotic resistance patterns is crucial for effective treatment.
  • Genetic diversity can influence bacterial adaptation and spread.

Purpose of the Study:

  • To determine antibiotic susceptibility profiles of canine S. pseudintermedius isolates.
  • To investigate the genetic polymorphism within these strains.
  • To assess the prevalence of methicillin-sensitive S. pseudintermedius (MSSP).

Main Methods:

  • Antibiotic susceptibility testing was performed on 39 canine S. pseudintermedius strains.
  • Genetic polymorphism was analyzed using pulsed-field electrophoresis (PFGE).
  • All isolates were confirmed as methicillin-sensitive S. pseudintermedius (MSSP).

Main Results:

  • Penicillin resistance was observed in 66.6% of strains, followed by neomycin (56.4%), erythromycin (53.8%), clindamycin (48.7%), chloramphenicol (48.7%), and tetracycline (46.2%).
  • Pulsed-field electrophoresis revealed significant genetic diversity among the S. pseudintermedius strains.
  • All 39 isolates were identified as methicillin-sensitive S. pseudintermedius (MSSP).

Conclusions:

  • Canine S. pseudintermedius exhibits high prevalence of resistance to common antibiotics like penicillin.
  • The genetic polymorphism suggests potential for adaptation and varied epidemiological characteristics.
  • Effective treatment strategies for canine S. pseudintermedius infections require careful consideration of local antibiotic resistance patterns.

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