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Nephrotic syndrome in elderly patients: three years experience at Siriraj Hospital
Manatchanok Jiratthawong1, Attapong Vongwiwatana, Kriengsak Vareesangthip
1Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Background:
The population age is being high and nephotic syndrome is a common renal disease.
Objective:
To find the etiology and clinical manifestations of nephrotic syndrome in the elderly patients who underwent renal biopsy at Siriraj hospital including management and outcome.
Material And Method:
Retrospective study in 76 nephrotic patients whose age > or =50 years and underwent renal biopsy between 2005-2007.
Results:
Seventy six nephrotic patients with age ranged from 50-84 years were analysed. Primary glomerulonephritis diseases were found more than secondary causes (5:2). The two most common glomerulonephritis were membranous GN and focal/segmental glomerulosclerosis. The etiology of common secondary GN was lupus nephtitis 11.84% following by diabetic nephropathy and amyloidosis. The patients received immunosuppressive drugs and complete response was found in 51%, partial response 10.2%, no response was 2% and no immunosuppressive therapy 36.7%. There was 1 patient died of septicaemia.
Conclusion:
Nephrotic syndrome in the elderly patients were not uncommon. The causes should be identified for prompt management and excellent outcome.
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