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Updated: May 31, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Chronic mesenteric ischemia: diagnosis and management
1Department of Cardiovascular Diseases, The John Ochsner Heart & Vascular Institute, Ochsner Clinic Foundation, New Orleans, LA 70121, USA. cwhite@ochsner.org
Abstract:
Chronic mesenteric ischemia (CMI) is the most common vascular disorder involving the intestines, however it is unusual in clinical practice. The redundancy of the visceral circulation with multiple interconnections between the superior mesenteric artery (SMA) and the inferior mesenteric artery (IMA) is the most likely explanation for the infrequent occurrence of CMI in clinical practice. Atherosclerosis is by the far the most common etiology of CMI. The increased utilization of diagnostic abdominal cross-sectional imaging has increased the recognition of atherosclerotic mesenteric stenoses. CMI is a clinical diagnosis, based upon symptoms and consistent anatomic findings. The classic setting for CMI is a female patient presenting with post-prandial abdominal discomfort that results in significant weight loss. Endovascular therapy with stenting has become the most common method chosen for revascularization having replaced open surgery with its associated morbidity and mortality.
Insights
Chronic mesenteric ischemia (CMI), a rare vascular intestinal disorder, is often caused by atherosclerosis. Diagnosis relies on symptoms and imaging, with endovascular stenting now the preferred treatment over open surgery.
Area of Science:
- Vascular Surgery
- Gastroenterology
- Diagnostic Imaging
Background:
- Chronic mesenteric ischemia (CMI) is the most common vascular intestinal disorder, yet infrequently diagnosed.
- The visceral circulation's extensive redundancy between the superior mesenteric artery (SMA) and inferior mesenteric artery (IMA) contributes to its rarity.
- Atherosclerosis is the predominant etiology of CMI.
Purpose of the Study:
- To review the clinical presentation, diagnosis, and management of chronic mesenteric ischemia.
- To highlight the increasing recognition of atherosclerotic mesenteric stenoses due to advanced imaging.
- To discuss the shift in treatment paradigms from open surgery to endovascular interventions.
Main Methods:
- Review of clinical presentation and diagnostic criteria for CMI.
- Analysis of the role of cross-sectional imaging in identifying mesenteric stenoses.
- Evaluation of treatment outcomes for endovascular therapy versus open surgery.
Main Results:
- CMI diagnosis is based on characteristic symptoms and anatomical findings.
- Post-prandial abdominal discomfort and weight loss are classic symptoms, particularly in female patients.
- Endovascular stenting is now the most common revascularization method, superseding open surgery due to lower morbidity and mortality.
Conclusions:
- Atherosclerotic CMI is increasingly recognized due to improved imaging techniques.
- Endovascular therapy offers a safer and more effective revascularization option for CMI.
- Understanding the clinical and anatomical features is crucial for timely diagnosis and management of CMI.
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