Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 31, 2026

A Modified Method for Heterotopic Mouse Heart Transplantion
11:29

A Modified Method for Heterotopic Mouse Heart Transplantion

Published on: June 23, 2014

Modified suture technique in a mouse heart transplant model.

Song Su1, Tobias R Türk, Shengli Wu

  • 1Department of Nephrology, University Hospital Essen, University of Duisburg-Essen, Germany.

Asian Journal of Surgery
|July 5, 2011
PubMed
Summary

A new suturing technique for mouse cardiac transplantation significantly reduces operation, warm ischemia, and re-beating times. This modified method improves anastomosis of the outflow tract in cardiac transplant models.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk-adapted HLA delisting and imlifidase-enabled deceased-donor kidney transplantation in highly sensitized kidney transplant candidates: a German expert consensus report.

Frontiers in immunology·2026
Same author

The International, Prospective COSMOS (CytOSorb® TreatMent Of Critically Ill PatientS) Registry: Interim Results in Patients with Septic Shock.

Annals of intensive care·2026
Same author

Are Adiponectin and Insulin Resistance Related to Stress Hyperglycaemia in Critically Ill Patients?

Indian journal of clinical biochemistry : IJCB·2026
Same author

The international, prospective COSMOS (CytOSorb® TreatMent Of Critically Ill PatientS) Registry: results from the first 300 patients.

Journal of anesthesia, analgesia and critical care·2026
Same author

Single-Center Experience With Complications and Clinical Outcomes of 464 Living Kidney Donors.

Transplantation proceedings·2026
Same author

Plasma Adsorption Perfusion (BR-350) Versus Open Albumin Dialysis (OPAL) for Hyperbilirubinemia in Hepatic Failure in Cirrhotic Patients.

Artificial organs·2026

Area of Science:

  • Surgical Innovation
  • Immunological Research
  • Transplantation Science

Background:

  • The mouse abdominal heart transplantation model is crucial for immunological studies.
  • A modified suturing technique using entire everting sutures for caval vein anastomosis was developed.
  • This study evaluates the efficacy of the modified technique compared to standard methods.

Purpose of the Study:

  • To assess the impact of a novel suturing technique on mouse cardiac transplantation outcomes.
  • To compare the modified technique with conventional methods regarding surgical efficiency and graft function.

Main Methods:

  • Isogenic abdominal heart transplantation was performed on 50 mice (25 per group).
  • Key metrics recorded included recipient operation time, caval anastomosis time, and graft warm ischemia time.

More Related Videos

Heterotopic Heart Transplantation in Mice
23:43

Heterotopic Heart Transplantation in Mice

Published on: July 19, 2007

Murine Cervical Heart Transplantation Model Using a Modified Cuff Technique
10:32

Murine Cervical Heart Transplantation Model Using a Modified Cuff Technique

Published on: October 12, 2014

Related Experiment Videos

Last Updated: May 31, 2026

A Modified Method for Heterotopic Mouse Heart Transplantion
11:29

A Modified Method for Heterotopic Mouse Heart Transplantion

Published on: June 23, 2014

Heterotopic Heart Transplantation in Mice
23:43

Heterotopic Heart Transplantation in Mice

Published on: July 19, 2007

Murine Cervical Heart Transplantation Model Using a Modified Cuff Technique
10:32

Murine Cervical Heart Transplantation Model Using a Modified Cuff Technique

Published on: October 12, 2014

  • Graft re-beating time and survival rates were monitored for 100 days post-transplantation.

    • Main Results:

    • The modified technique significantly reduced recipient operation time (40.7 vs. 44.3 min), caval anastomosis time (8.4 vs. 12.1 min), and warm ischemia time (23.4 vs. 27.2 min).
    • A statistically significant reduction in re-beating time was observed with the modified technique (1.2 vs. 1.5 min).
    • Fewer surgical complications were noted in the modified group, with no significant difference in survival rates.

    Conclusions:

    • The novel suturing technique simplifies outflow tract anastomosis in mouse cardiac transplantation.
    • This method leads to significant reductions in critical surgical parameters, enhancing procedural efficiency.
    • The modified technique offers a valuable improvement for mouse cardiac transplantation models in immunological research.