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Related Experiment Video

Updated: May 31, 2026

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice
07:17

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice

Published on: June 22, 2016

Current knowledge on porcine regulatory T cells.

Tobias Käser1, Wilhelm Gerner, Kerstin Mair

  • 1Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210 Vienna, Austria. tobias.kaeser@vetmeduni.ac.at

Veterinary Immunology and Immunopathology
|July 5, 2011
PubMed
Summary

Regulatory T cells (Tregs) in swine are a developing research area. This review summarizes current knowledge on porcine Tregs, including their phenotype, function, and role in disease and transplantation.

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Area of Science:

  • Immunology
  • Veterinary Science

Background:

  • Regulatory T cells (Tregs) are crucial for immune homeostasis in humans and mice, with extensive research over 15 years.
  • Porcine Tregs were first identified in 2008, and research in this area is still in its early stages.
  • Existing studies provide foundational knowledge on Treg phenotype, suppressive mechanisms, and targets in swine.

Purpose of the Study:

  • To provide a concise overview of the current understanding of regulatory T cells in swine.
  • To consolidate available information on porcine Treg characteristics and functions.

Main Methods:

  • Literature review of studies on porcine regulatory T cells.
  • Synthesis of data on Treg phenotype, function, and implications in swine.

Main Results:

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Determination of Regulatory T Cell Subsets in Murine Thymus, Pancreatic Draining Lymph Node and Spleen Using Flow Cytometry
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Determination of Regulatory T Cell Subsets in Murine Thymus, Pancreatic Draining Lymph Node and Spleen Using Flow Cytometry

Published on: February 27, 2019

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Last Updated: May 31, 2026

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice
07:17

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice

Published on: June 22, 2016

Determination of Regulatory T Cell Subsets in Murine Thymus, Pancreatic Draining Lymph Node and Spleen Using Flow Cytometry
08:06

Determination of Regulatory T Cell Subsets in Murine Thymus, Pancreatic Draining Lymph Node and Spleen Using Flow Cytometry

Published on: February 27, 2019

  • Basic information on porcine Treg phenotype and suppressive mechanisms is emerging.
  • Porcine Tregs have implications in transplantation and certain disease states.
  • Research on swine Tregs is less advanced compared to human and mouse models.

Conclusions:

  • The field of porcine regulatory T cell research is expanding.
  • Further investigation is needed to fully elucidate the role of Tregs in swine immunity, disease, and transplantation.
  • Understanding porcine Tregs is vital for advancing veterinary immunology and related applications.