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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
A new prize system for drug innovation
Afschin Gandjour1, Nadja Chernyak
1Department of Public Health, Faculty of Medicine, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany. gandjour@gmx.com
A novel drug innovation prize system rewards based on health benefits, using cost-effectiveness to value health. This approach incentivizes research and development for social value, offering an alternative to patents.
Area of Science:
- Health Economics
- Pharmaceutical Policy
- Innovation Management
Background:
- Current pharmaceutical patent systems may not fully align innovator rewards with societal health benefits.
- Information asymmetry regarding drug value and potential overuse complicates reward determination.
Purpose of the Study:
- To propose a new prize (reward) system for drug innovation.
- To establish a system that bases rewards on the quantified value of health benefits over time.
- To create optimal incentives for research and development (R&D) investment.
Main Methods:
- Developing a reward system where payment is contingent on accrued health benefits.
- Determining the willingness to pay for a unit of health benefit using cost-effectiveness ratios from palliative/nursing care.
- Mathematically linking reward size to information uncertainty, including potential drug overuse, to address information gaps.
Main Results:
- The proposed system rewards drug innovators based on the social value of their innovations.
- It provides optimal incentives for R&D by aligning rewards with societal impact.
- The system aims to mitigate excessive marketing by both innovators and generic drug producers.
Conclusions:
- The proposed prize system offers a viable, non-voluntary alternative to the current patent system.
- It ensures that rewards accurately reflect the true health benefits and social value of drug innovations.
- This model promotes more efficient and socially beneficial drug development.
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