Related Experiment Video
Updated: May 31, 2026

Reduced Procedure Time and Variability with Active Esophageal Cooling During Radiofrequency Ablation for Atrial Fibrillation
Published on: August 25, 2022
The management and outcome of documented intraoperative heart rate-related electrocardiographic changes
Ion A Hobai1, Cosmin Gauran, Hovig V Chitilian
1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Insights
Heart rate-related ECG changes (REC) during surgery are often precipitated by anesthesia events. Prompt heart rate reduction effectively manages REC, with low rates of postoperative myocardial infarction and confirmed coronary artery disease.
Area of Science:
- Cardiology
- Anesthesiology
- Cardiac Electrophysiology
Background:
- Electrocardiographic (ECG) signs of cardiac ischemia can be precipitated by heart rate increases, termed heart rate-related ECG changes (REC).
- Understanding the incidence, specificity for coronary artery disease (CAD), and outcomes of REC is crucial for surgical patient management.
Observation:
- A retrospective chart review of 158,252 anesthesia records identified 26 cases of REC.
- REC was frequently triggered by anesthesia-related events such as intubation, extubation, and bradycardia treatment.
Findings:
- Prompt management by reducing heart rate with beta-blockers, opioids, or cardioversion, alongside stimulus removal, resolved REC in 24 cases.
- Only one patient developed postoperative myocardial infarction when REC persisted.
- Subsequent cardiology evaluation confirmed clinically significant CAD in a minority of patients.
Implications:
- The reported incidence of REC is lower than expected, suggesting many events may go unrecognized.
- Effective management of REC can prevent adverse cardiac events during surgery.
- REC may not always indicate significant underlying coronary artery disease, warranting careful diagnostic workup.
Objectives:
The authors analyzed surgical cases in which electrocardiographic (ECG) signs of cardiac ischemia were noted to be precipitated by increases in heart rate (ie, heart rate-related ECG changes [REC]). The authors aimed to find REC incidence, specificity for coronary artery disease (CAD), and the outcome associated with different management strategies.
Design:
A retrospective review.
Setting:
A university hospital, tertiary care.
Participants:
Patients undergoing surgery under anesthesia.
Interventions:
A chart review.
Measurements:
The authors searched 158,252 anesthesia electronic records for comments noting REC (ie, ST-segment or T-wave changes). After excluding cases with potentially confounding conditions (eg, hypotension, hyperkalemia, and so on), 26 cases were analyzed.
Results:
REC commonly was precipitated by anesthesia-related events (ie, intubation, extubation, and treatment of bradycardia). In 24 cases, REC was managed by prompt heart rate reduction using β-blocker agents, opioids, and/or cardioversion in the addition to the removal of stimulus. Only 1 case had a copy of the ECG printed. Two cases were aborted, 1 was shortened and 23 proceeded without change. Postoperative troponin T levels were checked, and cardiology consultation was obtained in selected cases and led to further cardiac evaluation in 6 cases. Postoperative myocardial infarction developed in only 1 patient in whom the ECG changes were allowed to persist throughout the case.
Conclusions:
This incidence of reported REC was much lower than the previously reported incidence of ischemia-related ECG changes, suggesting that the largest proportion of events go unnoticed. In many patients, subsequent cardiology workup did not confirm the existence of clinically significant CAD.
Related Concept Videos
Pulse rhythm
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Electrocardiogram
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...
Dysrhythmias VII: Nursing Management of Dysrhythmias
Dysrhythmias V: Evaluating Dysrhythmias
Cardiopulmonary Resuscitation IV: Pharmacological Management
