Related Experiment Videos
[Inflammatory myoglandular polyp (Nakamura polyp): a case report].
J A Vázquez-Reta1, E Tarango-González, R Fierro-Murga
1Servicio de Cirugía Endoscópica, Hospital Central Universitario, Universidad Autónoma de Chihuahua, Chihuahua, México. dr_vazquezreta@hotmail.com
Revista De Gastroenterologia De Mexico
|July 5, 2011
Summary
Inflammatory myoglandular polyps (IMGPs) are rare, benign large bowel polyps. This case highlights IMGP mimicking adenocarcinoma, emphasizing the need for accurate pathological diagnosis.
Area of Science:
- Gastroenterology
- Colorectal Surgery
- Surgical Pathology
Background:
- Inflammatory myoglandular polyps (IMGPs) are rare, non-neoplastic lesions of the large bowel.
- They are characterized by inflammatory granulation tissue, smooth muscle proliferation, and hyperplastic glands.
- Etiology is unclear but linked to chronic inflammation, fecal stasis, and abnormal colonic motility.
Observation:
- IMGPs can be asymptomatic or present with hematochezia.
- Endoscopic appearance may resemble other colorectal polyps, including adenocarcinomas.
- This case involved a 33-year-old male presenting with hematochezia due to an IMGP.
Findings:
- The IMGP was initially misdiagnosed as well-differentiated adenocarcinoma.
- Final pathological examination confirmed the diagnosis of IMGP.
- Surgical resection of the IMGP led to the resolution of hematochezia.
Implications:
- Accurate pathological diagnosis is crucial for differentiating IMGPs from malignant colorectal neoplasms.
- Understanding the endoscopic and pathological features of IMGP aids in appropriate patient management.
- Resection is an effective treatment for symptomatic IMGPs, resolving bleeding complications.
Related Concept Videos
Inflammatory Bowel Disease III: Crohn's Disease
Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease II: Ulcerative Colitis
Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Inflammatory Bowel Disease II: Crohn's Disease
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Gastritis III: Clinical Manifestations and Management
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Inflammatory Bowel Disease IV: Clinical Manifestations
Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...
Appendicitis
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...