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Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
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Related Experiment Video

Updated: May 31, 2026

How to Create Conditioned Taste Aversion for Grazing Ground Covers in Woody Crops with Small Ruminants
05:55

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Peste des petits ruminants: a suitable candidate for eradication?

M D Baron1, S Parida, C A L Oura

  • 1Institute for Animal Health, Ash Road, Pirbright, Surrey GU24 0NF. baron@bbsrc.ac.uk

The Veterinary Record
|July 5, 2011
PubMed
Summary
This summary is machine-generated.

Rinderpest, the cattle plague, is being eradicated. This success prompts an evaluation of targeting peste des petits ruminants (PPR), a related virus, for global eradication.

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Last Updated: May 31, 2026

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Area of Science:

  • Veterinary Virology
  • Disease Eradication

Background:

  • Rinderpest, a historically devastating cattle plague, is nearing global eradication.
  • The last remaining rinderpest virus (RPV) is contained in laboratories and vaccine stockpiles.

Purpose of the Study:

  • To assess the feasibility and justification for global eradication of peste des petits ruminants (PPR).
  • To evaluate PPR as a candidate for eradication following the success with RPV.

Main Methods:

  • Review of historical RPV eradication efforts.
  • Analysis of PPR epidemiology and impact on small ruminants.
  • Assessment of current PPR control strategies and potential eradication pathways.

Main Results:

  • Rinderpest eradication represents a significant milestone in veterinary public health.
  • Peste des petits ruminants (PPR) poses a substantial threat to small ruminant populations globally.
  • Existing knowledge from RPV eradication can inform PPR control.

Conclusions:

  • The eradication of rinderpest provides a precedent for targeting other viral diseases.
  • Peste des petits ruminants (PPR) presents a viable target for global eradication efforts.
  • Further research and strategic planning are necessary to achieve PPR eradication.