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Related Concept Videos

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Autism Spectrum Disorder

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Related Experiment Video

Updated: May 31, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

Distinctive neural processes during learning in autism.

Sarah E Schipul1, Diane L Williams, Timothy A Keller

  • 1Department of Psychology, Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, PA 15213, USA. schipul@cmu.edu

Cerebral Cortex (New York, N.Y. : 1991)
|July 5, 2011
PubMed
Summary
This summary is machine-generated.

Individuals with autism show altered brain connectivity during social learning. This study found reduced functional and structural connectivity in autism, impacting the brain's ability to adapt and learn social cues.

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Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

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Related Experiment Videos

Last Updated: May 31, 2026

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Published on: September 12, 2011

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09:13

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05:32

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

Published on: December 7, 2018

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Cognitive Science

Background:

  • Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by social communication deficits.
  • Understanding the neural underpinnings of social learning in autism is crucial for developing targeted interventions.

Purpose of the Study:

  • To compare neural activation and connectivity patterns during social learning in high-functioning individuals with autism and neurotypical controls.
  • To investigate the relationship between structural and functional brain connectivity and learning in autism.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) was used to assess brain activity and functional connectivity.
  • Participants learned a social judgment task involving identifying liars from avatar expressions.
  • Structural connectivity was measured by corpus callosum size.

Main Results:

  • The autism group exhibited similar behavioral learning to controls but showed reduced activation in cortical association areas.
  • A smaller increase in functional connectivity was observed in the autism group during learning.
  • Decreased structural connectivity (corpus callosum size) in autism correlated with functional connectivity measures.

Conclusions:

  • Cortical underconnectivity in autism may limit the brain's capacity for rapid adaptation during social learning.
  • Findings suggest that altered connectivity patterns are a key feature of social learning differences in autism.