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Updated: May 31, 2026

Adaptation of Semiautomated Circulating Tumor Cell (CTC) Assays for Clinical and Preclinical Research Applications
Published on: February 28, 2014
Circulating tumor cells count and characterization in a male breast cancer patient
Paola Gazzaniga1, Giuseppe Naso, Cristina Raimondi
1Department of Molecular Medicine,apienza University of Rome, Rome, Italy. paola.gazzaniga@uniroma1.it
Abstract:
A 64-y-old man presented to Medical Oncology Department a metastatic invasive ductal breast carcinoma, positive for estrogen (ER) and progesterone receptors (PR) and Her2/neu negative. The patient was treated with different lines of therapy, with rapid radiological progression of disease. After four courses of a third-line chemotherapy, a radiological stable disease was maintained. The patient was followed by serial blood drawings for the characterization and count of circulating tumor cells (CTC). This is the first report concerning the predictive and prognostic value of CTC in a male breast cancer patient.
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