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Updated: May 31, 2026

Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules
08:15

Bead Aggregation Assays for the Characterization of Putative Cell Adhesion Molecules

Published on: October 17, 2014

The SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motility

C H Benes1, G Poulogiannis, L C Cantley

  • 1Department of Medicine, Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

Oncogene
|July 5, 2011
PubMed
Summary

Increased tyrosine phosphorylation of CDCP1 (CUB Domain-Containing Protein-1) and SRC-family kinases (SFKs) correlates with decreased FAK phosphorylation in lung tumors. This suggests a novel mechanism for CDCP1/SFK in regulating cell adhesion and motility during metastasis.

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