Neurologic complications of acute and chronic renal failure

It is obvious from the preceding discussion that neurologic complications contribute significantly to morbidity and mortality in patients with chronic and acute renal failure and that dysfunction of the nervous system continues to occur even in those patients receiving successful renal transplants. In an effort to find the causes of these disorders, a large cooperative study of patients with renal failure will be needed to supply valid and statistically significant data that can be used to test the hypotheses suggested by this and other review papers. At the present time, the data are limited, because in almost all instances small and biased series of patients have been used, and basic criteria of disease have not been standardized. It will be a large task to correct these deficiencies, but it is definitely one that should be undertaken in the near future.