Related Experiment Video
Updated: May 31, 2026

Catheterization of the Carotid Artery and Jugular Vein to Perform Hemodynamic Measures, Infusions and Blood Sampling in a Conscious Rat Model
Published on: January 30, 2015
A comparison between blood flow outcomes of tunneled external jugular and internal jugular hemodialysis catheters
Hemender S Vats1, Janet Bellingham, Jason W Pinchot
1Section of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 52713, USA. hvats@uwhealth.org
Insights
The external jugular (EJ) vein offers comparable blood flow outcomes to the right and left internal jugular (IJ) veins for hemodialysis (HD) catheters. This study suggests EJ vein placement is a viable option for long-term venous access.
Area of Science:
- Nephrology
- Vascular Access
- Medical Devices
Background:
- The right internal jugular (RIJ) vein is typically preferred for long-term hemodialysis (HD) central venous catheters (CVC).
- Left internal jugular (LIJ) vein use may compromise future arteriovenous fistula/graft (AVF/AVG) placement due to central venous stenosis.
- The right external jugular (EJ) vein presents a potential alternative access site.
Purpose of the Study:
- To compare the blood flow outcomes of percutaneously placed EJ, LIJ, and RIJ HD catheters.
- To evaluate the efficacy of EJ vein catheterization as a long-term HD access modality.
Main Methods:
- A prospectively collected database of 46 hemodialysis patients receiving tunneled catheters over 4 years was analyzed.
- Blood flow outcomes of date-matched RIJ, LIJ, and EJ catheters were compared at 30 and 90 days.
- Analysis of Covariance (ANOVA) and multiple regression were used to assess outcomes and influencing factors.
Main Results:
- No significant difference in 90-day blood flow outcomes was observed among the RIJ, LIJ, and EJ catheter groups.
- Thirty-day blood flow measurements were comparable across the three groups (RIJ: 348.5±56.62, LIJ: 341±22.42, EJ: 365.7±71.76 mL/min).
- No patient covariates (age, sex, race, diabetes) were associated with 30- or 90-day blood flow outcomes.
Conclusions:
- External jugular vein (EJ) catheter blood flow outcomes at 30 and 90 days are comparable to historical data for LIJ and RIJ catheters.
- EJ CVC placement demonstrates potential as an alternative long-term hemodialysis access.
- Further prospective studies are warranted to establish the role of EJ CVC placement.
Purpose:
The right internal jugular (RIJ) vein is preferred for placement of long-term venous catheters (CVC) for hemodialysis (HD). Use of left IJ vein potentially depletes the access site for arteriovenous fistula (AVF) or arteriovenous graft (AVF) placement because of the high rates of central venous stenosis. The right external jugular (EJ) vein is a viable alternative to the LIJ. The purpose of this study is to compare blood flow outcomes in a series of percutaneously placed external jugular (EJ), LIJ and RIJ HD catheters.
Methods:
Using a prospectively collected database, we identified 46 hemodialysis patients who received a tunneled catheter during a 4-year period. Blood flow outcomes of RIJ, LIJ, and EJ catheters that were date-matched over the study period were compared. Using ANOVA, the blood flow outcomes of the 3 tunneled catheter techniques at 30-d and 90-d were compared.
Results:
The 90-d blood flow outcomes of the 3 groups did not differ significantly. The 30-d blood flow was found to be 348.5± 56.62, 341± 22.42, and 365.7± 71.76 mL/min for RIJ, LIJ, and EJ respectively (P<.05). Using multiple regression analysis, no covariates (age, sex, race, diabetes) were found to be associated with blood flow outcomes at 30-d or 90-d. No identifiable factors were found to be associated with the difference in blood flow between 30-d and 90-d either.
Conclusions:
EJ blood flow outcomes at 30-d and 90-d were comparable to both LIJ and RIJ historic data. Further prospective investigation is required to define the role of EJ CVC placement as another potential long-term access modality.
Related Concept Videos
Hemodialysis I: Introduction
Hemodialysis II: Procedure and Complications
Hemodialysis III: Nursing Management
Cardiac Catheterization II: Right Heart Catheterization
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy
Continuous Renal Replacement Therapy

